منابع مشابه
Photodynamic DNA damage mediated by δ-aminolevulinic acid-induced porphyrins
P.Duez1, M.Hanocq and J.Dubois series of exogenous photosensitizers have been determined. For those exposure conditions in which no exogenous sensitizers Institut de Pharmacie, Service de Chimie Bioanalytique, de Toxicologie et are added, a radical-mediated mechanism of carcinogenicity, de Chimie Physique Appliquée, Université Libre de Bruxelles, CP 205/1, however, supposes endogenous sensitize...
متن کاملCritical Dose of Lead Affecting δ-Aminolevulinic Acid Levels
Critical Dose of Lead Affecting δAminolevulinic Acid Levels: Katsuyuki MURATA, et al. Akita University School of Medicine—To estimate the critical dose of the association between the blood lead concentration (BPb) and δ-aminolevulinic acid (ALA) levels, ALA levels in plasma (ALA-P), blood (ALAB), and urine (ALA-U), and the activity of δaminolevulinic acid dehydratase (ALAD) were determined in 1...
متن کاملBone marrow delta-aminolevulinic acid synthetase activity in hematological disorders.
An improved radiochemical method to measure the o-aminoJevulinic acid (ALA) synthetase activity in human bone marrow erythroblasts by incubating bone marrow cell homogenate with 14C-succinate and succinyl CoA generating system has been reported. Studies were made to obtain the optimal conditions for the enzyme assay and to confirm the reliability of the assay procedures. ALA-synthetase in eryth...
متن کاملA Sensitive Radiochemical Assay Method for s=Aminolevulinic Acid Synthetase*
1. A new sensitive method for measuring &aminolevulinic acid (ALA) synthetase activity has been developed based on the incorporation of 14C-succinate into ALA. The method is extremely sensitive and will permit assay of the enzyme in normal tissues and in small amounts of tissue for which the existing calorimetric methods are inadequate. Difficulties due to aminoacetone synthesis are eliminated....
متن کاملs=Aminolevulinic Acid Synthetase I. STUDIES IN LIVER HOMOGENATES
6-Aminolevulinic acid synthesis has been demonstrated in both porphyric and normal liver homogenates. A study of the factors which affect &aminolevulinic acid production indicates that the enzyme b-aminolevulinic acid synthetase can be measured in liver homogenates, with use of added glycine and endogenously generated succinyl coenzyme A. 6Aminolevulinic acid production in this system is greate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1970
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)63141-2